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Your doctor may prescribe BYETTA along with Lantus (insulin glargine), which is
a long-acting insulin, to help improve your blood sugar control.
When taken with Lantus, a clinical study showed that:
- Patients taking BYETTA and Lantus reduced their overall A1C compared to patients
taking Lantus alone. An A1C blood test determines a patient’s blood sugar control
by providing a 3-month average of blood sugar levels. An A1C under 7% meets the
American Diabetes Association Guidelines.
- BYETTA helped 57% of patients achieve an A1C level of less than 7% compared
with 30% of those taking Lantus alone.
- Although BYETTA is not a weight-loss product, it may reduce the amount of food you eat. On average, patients who used the 10-microgram dose of BYETTA,
in combination with certain diabetes pills or Lantus, lost 4 pounds over 30 weeks compared with those on Lantus alone who gained an average
of 2 pounds in 30 weeks.
- Some common side effects that occurred more often in patients taking BYETTA
with Lantus than in patients taking Lantus alone include nausea, vomiting, diarrhea,
headache, constipation, and weakness.
BYETTA is not insulin and should not be taken instead of insulin. BYETTA is not
recommended to be taken with short- and/or rapid-acting insulin.
Better blood sugar control
BYETTA and Lantus work in 2 different ways toward the same goal: helping you control
your blood sugar. When you have type 2 diabetes, your blood sugar is usually higher
at 2 key times: right after a meal—and then throughout the day. BYETTA helps lower
your blood sugar, especially after your meals. Lantus helps keep your blood sugar
from increasing between meals.
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BYETTA is an injectable prescription medicine that may improve blood sugar (glucose) control in adults with type 2 diabetes mellitus, when used with a diet and exercise program.
BYETTA is not insulin and should not be taken instead of insulin. BYETTA can be used with Lantus® (insulin glargine), which is a long-acting insulin, but should not be taken with short- and/or rapid-acting insulin. BYETTA is not for people with type 1 diabetes or people with diabetic ketoacidosis.
Important Safety Information for BYETTA® (exenatide) injection
- Serious side effects can happen in people who take BYETTA, including inflammation of the pancreas (pancreatitis) which may be severe and lead to death. Before taking BYETTA, tell your healthcare provider if you have had pancreatitis, stones in your gallbladder (gallstones), a history of alcoholism, or high blood triglyceride levels. Call your healthcare provider right away if you have pain in your stomach area (abdomen) that is severe, and will not go away. The pain may happen with or without vomiting and may be felt going from your abdomen through to your back.
- Your risk for getting low blood sugar is higher if you take BYETTA with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. The dose of your sulfonylurea or insulin medicine may need to be lowered while you use BYETTA.
- BYETTA should not be used in people who have severe kidney problems and should be used with caution in people who have had a kidney transplant. BYETTA may cause new or worse problems with kidney function, including kidney failure.
- Before you use BYETTA, tell your healthcare provider if you have severe problems with your stomach, such as delayed emptying of your stomach (gastroparesis) or problems with digesting food.
- Do not use BYETTA if you have had an allergic reaction to exenatide or any of the other ingredients in BYETTA. Severe allergic reactions can happen with BYETTA. Stop taking BYETTA and get medical help right away.
- Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if BYETTA will harm your unborn baby. Talk to your healthcare provider first if you are breastfeeding or plan to breastfeed.
- The most common side effects with BYETTA include nausea, vomiting, diarrhea, feeling jittery, dizziness, headache, acid stomach, constipation, and weakness. Nausea most commonly happens when first starting BYETTA, but may become less over time.
These are not all the side effects with BYETTA. Talk to your healthcare provider about any side effect that bothers you or that does not go away.
Please see the BYETTA Prescribing Information and Medication Guide.
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