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How to Take BYETTA

The BYETTA Injection Pen is available in 2 dose strengths: 5 micrograms (mcg) and 10 mcg. Your healthcare provider will decide which dose is right for you, and help you learn how to inject BYETTA before you use it for the first time.

  • Each pen contains enough medicine for 1 injection 2 times a day for 30 days
  • BYETTA should be started at 5 mcg twice daily. Based on clinical response, the dose can be increased to 10 mcg twice daily after 1 month of treatment. Starting with 5 mcg reduces the incidence and severity of gastrointestinal side effects

Explore the tabs below to learn more about BYETTA.

Where to inject BYETTA

Inject your dose of BYETTA under the skin (subcutaneous injection) of your upper leg (thigh), stomach area (abdomen), or upper arm as instructed by your healthcare provider. Do not inject into a vein or muscle.

  • Use BYETTA exactly as prescribed by your healthcare provider. Do not change your dose unless your healthcare provider has told you to change your dose.
  • Your healthcare provider must teach you how to inject BYETTA before you use it for the first time. If you have questions or do not understand the instructions, talk to your healthcare provider or pharmacist.
  • Pen needles are not included. You may need a prescription to purchase pen needles from your pharmacist. Ask your healthcare provider which needle length and gauge are best for you.
  • Do not mix BYETTA and insulin in the same syringe or vial, even if you take them at the same time.
  • Do not share your BYETTA Pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.
  • See the Pen User Manual that comes with BYETTA for instructions for using the Pen and injecting BYETTA.

When to take BYETTA

BYETTA is injected 2 times a day, at any time within the 60 minutes (1 hour) before your morning and evening meals (or before the 2 main meals of the day, approximately 6 hours or more apart. Do not take BYETTA after your meal.

  • If you miss a dose of BYETTA, skip that dose and take your next dose at the next prescribed time. Do not take an extra dose or increase the amount of your next dose to make up for a missed dose.
  • If you use too much BYETTA, call your healthcare provider or poison control center at 1-800-222-1222 right away. Too much BYETTA can cause your blood sugar to drop quickly, and you may have symptoms of low blood sugar. You may need medical treatment right away. Too much BYETTA can also cause severe nausea and vomiting.
Example injection schedule for BYETTA
Single Patient Use Only

How to store and handle BYETTA

It is important that you carefully follow all storage instructions for BYETTA. The Instructions for Use do not take the place of talking with your healthcare provider. If you are having problems using your BYETTA Pen, call our toll-free Customer Support Center at 1-800-236-9933 for additional support and guidance.

Storage

  • Prior to first use, store your new unused BYETTA Pen in the original carton in a refrigerator at 36°F to 46°F (2°C to 8°C).
  • After first use, your BYETTA Pen can be kept at room temperature not to exceed 77°F (25°C).
  • Do not freeze. Do not use BYETTA if it has been frozen. BYETTA should be protected from light.
  • When carrying the pen away from home, store the pen at a temperature between 36°F and 77°F (2°C to 25°C) and keep dry.
  • Do not store your BYETTA Pen with the needle attached. If the needle is left on the pen, BYETTA may leak from the pen and air bubbles may form in the cartridge.
  • Keep your pen and needles out of the reach of children.

How long can I use a BYETTA Pen?

  • You can use your BYETTA Pen for up to 30 days after setting up a new pen for first use. After 30 days, throw away the BYETTA Pen, even if it is not completely empty.
  • Write down the date when you first used your pen and the date 30 days later to discard the pen.
  • BYETTA should not be used after the expiration date printed on the pen label.

How do I clean my BYETTA Pen?

  • Wipe the outside of the pen with a clean, damp cloth.
  • White particles may appear on the outside tip of the cartridge during normal use. You may remove them with an alcohol wipe or alcohol swab.

How do I throw away my needles?

  • Do not throw away the pen with a needle attached.
  • Place used needles in a closeable, puncture-resistant container. You may use a sharps container (such as a red biohazard container), a hard plastic container (such as a detergent bottle), or a metal container (such as an empty coffee can). Ask your healthcare provider for instructions on the right way to throw away (dispose of) your used pens and the container. There may be state and local laws about how you should throw away used pens and needles.
  • Do not throw the disposal container in the household trash. Do not recycle.
  • Always keep the puncture-proof container out of the reach of children.

Do not share your BYETTA Pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Be sure to read the Instructions for Use that comes with your BYETTA Pen for more complete instructions.

Important notes

BYETTA Customer Support Center
The BYETTA pen is for single patient use only
  • Do not share your BYETTA Pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.
  • Do not reuse or share needles with another person.
  • Be sure to read the Instructions for Use that comes with your BYETTA Pen for more complete instructions.
  • Follow your healthcare provider’s instructions for diet, exercise, and how often to test your blood sugar. If you see your blood sugar increasing during treatment with BYETTA, talk to your healthcare provider because you may need to adjust your current treatment plan for your diabetes.
  • Talk to your healthcare provider about how to manage high blood sugar (hyperglycemia) and low blood sugar (hypoglycemia), and how to recognize problems that can happen with your diabetes.

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BYETTA Pen Instructions for Use

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